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SynPharm is a database of ligand-responsive protein sequences, derived from interactions from the Guide to PHARMACOLOGY and using data from the Protein Data Bank.
'Bind sequences' are obtained by identifying key binding residues on target proteins interating with a ligand.
The sequences can be used to confer druggability to a synthetic protein, and each contain metrics such as atomic contact ratio, proportional length and residue distance matrices.
Our third database release of 2016, version 2016.3 was published on 21st July 2016. Follow the link below to the release blog for further details.
A FREE publication snapshot created from the database summary pages.
Please see the 4 minute introductory video on the Concise Guide:
The IUPHAR/BPS Guide to PHARMACOLOGY builds upon and replaces the original IUPHAR Committee on Receptor Nomenclature and Drug Classification Database (IUPHAR-DB)