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Bronchial asthma

Disease ID:164
Name:Bronchial asthma
Associated with:1 target

Targets

BLT1 receptor
References:  1-6

Ligands

No ligand related data available for Bronchial asthma

References

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1. Miyahara N, Ohnishi H, Matsuda H, Miyahara S, Takeda K, Koya T, Matsubara S, Okamoto M, Dakhama A, Haribabu B et al.. (2008) Leukotriene B4 receptor 1 expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness. J. Immunol., 181 (2): 1170-8. [PMID:18606670]

2. Miyahara N, Takeda K, Miyahara S, Matsubara S, Koya T, Joetham A, Krishnan E, Dakhama A, Haribabu B, Gelfand EW. (2005) Requirement for leukotriene B4 receptor 1 in allergen-induced airway hyperresponsiveness. Am. J. Respir. Crit. Care Med., 172 (2): 161-7. [PMID:15849325]

3. Miyahara N, Takeda K, Miyahara S, Taube C, Joetham A, Koya T, Matsubara S, Dakhama A, Tager AM, Luster AD et al.. (2005) Leukotriene B4 receptor-1 is essential for allergen-mediated recruitment of CD8+ T cells and airway hyperresponsiveness. J. Immunol., 174 (8): 4979-84. [PMID:15814727]

4. Taube C, Miyahara N, Ott V, Swanson B, Takeda K, Loader J, Shultz LD, Tager AM, Luster AD, Dakhama A et al.. (2006) The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness. J. Immunol., 176 (5): 3157-64. [PMID:16493075]

5. Terawaki K, Yokomizo T, Nagase T, Toda A, Taniguchi M, Hashizume K, Yagi T, Shimizu T. (2005) Absence of leukotriene B4 receptor 1 confers resistance to airway hyperresponsiveness and Th2-type immune responses. J. Immunol., 175 (7): 4217-25. [PMID:16177061]

6. Toda A, Terawaki K, Yamazaki S, Saeki K, Shimizu T, Yokomizo T. (2010) Attenuated Th1 induction by dendritic cells from mice deficient in the leukotriene B4 receptor 1. Biochimie, 92 (6): 682-91. [PMID:20004699]