Aldosterone-producing adenoma

Disease ID:50
Name:Aldosterone-producing adenoma
Associated with:1 targets
0 immuno-relevant targets
0 immuno-relevant ligands
Database Links
Orphanet: ORPHA85142

Targets

Cav1.3
Role:  Hyperaldosteronism with adrenal hypertension
References:  1-2
Mutations:  Cav1.3 is associated with 9 mutation. Click here for details

Ligands

No ligand related data available for Aldosterone-producing adenoma

References

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1. Azizan EA, Poulsen H, Tuluc P, Zhou J, Clausen MV, Lieb A, Maniero C, Garg S, Bochukova EG, Zhao W et al.. (2013) Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension. Nat. Genet., 45 (9): 1055-60. [PMID:23913004]

2. Scholl UI, Goh G, Stölting G, de Oliveira RC, Choi M, Overton JD, Fonseca AL, Korah R, Starker LF, Kunstman JW et al.. (2013) Somatic and germline CACNA1D calcium channel mutations in aldosterone-producing adenomas and primary aldosteronism. Nat. Genet., 45 (9): 1050-4. [PMID:23913001]