Arterial hypertension

Disease ID:82
Name:Arterial hypertension
Associated with:1 targets
0 immuno targets
0 immuno ligands

Targets

Cav1.2
Drugs:  Nifedipine, amlodipine and other DHPs, verapamil, diltiazem
Side effects:  Hypotension, edema, constipation, bradycardia, AV-block.
Therapeutic use:  Treatment of hypertension (first-line option).
References:  1-2

Ligands

No ligand related data available for Arterial hypertension

References

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1. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. (2002) Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA.288: 2981-97. [PMID:12479763]

2. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, Jones DW, Materson BJ, Oparil S, Wright JT, Roccella EJ. (2003) Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. Hypertension42 (6): 1206-52. [PMID:14656957]