Taste 2 receptors C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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The composition and stoichiometry of bitter taste receptors is not yet established. Bitter receptors appear to separate into two groups, with very restricted ligand specificity or much broader responsiveness. For example, T2R5 responded to cycloheximide, but not 10 other bitter compounds [2], while T2R14 responded to at least eight different bitter tastants, including (-)-α-thujone and picrotoxinin [1].

Specialist database BitterDB contains additional information on bitter compounds and receptors [5].

Receptors

TAS2R1 C Show summary »

TAS2R3 C Show summary »

TAS2R4 C Show summary »

TAS2R5 C Show summary »

TAS2R7 C Show summary »

TAS2R8 C Show summary »

TAS2R9 C Show summary »

TAS2R10 C Show summary »

TAS2R13 C Show summary »

TAS2R14 C Show summary »

TAS2R16 C Show summary »

TAS2R19 C Show summary »

TAS2R20 C Show summary »

TAS2R30 C Show summary »

TAS2R31 C Show summary »

TAS2R38 C Show summary »

TAS2R39 C Show summary »

TAS2R40 C Show summary »

TAS2R41 C Show summary »

TAS2R42 C Show summary »

TAS2R43 C Show summary »

TAS2R45 C Show summary »

TAS2R46 C Show summary »

TAS2R50 C Show summary »

TAS2R60 C Show summary »

References

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How to cite this family page

Database page citation:

Taste 2 receptors. Accessed on 13/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=117.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Christopoulos A, Davenport AP, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: G protein-coupled receptors. Br J Pharmacol. 174 Suppl 1: S17-S129.