ABCD subfamily of peroxisomal ABC transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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This family of 'half-transporters' act as homo- or heterodimers to transport various metabolites across the peroxisomal membrane, whcih include: very long-chain fatty acid-CoA esters, pristanic acid, di- and trihydroxycholestanoic acid, dicarboxylic acids and tetracosahexaenoic acid [3].

Transporters

ALDP (ABCD1) C Show summary »

ALDR (ABCD2) C Show summary »

PMP70 (ABCD3) C Show summary »

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References

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How to cite this family page

Database page citation:

ABCD subfamily of peroxisomal ABC transporters. Accessed on 19/08/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=154.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172: 6110-6202.