V-type ATPase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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The V-type ATPase is most prominently associated with lysosomes in mammals, but also appears to be expressed on the plasma membrane and neuronal synaptic vesicles.

The V1 motor, responsible for ATP turnover, has eight subunits with a composition of A-H.

The V0 motor, responsible for ion translocation, has six subunits (a-e).

Transporters

Complexes

V-type ATPase V1 motor Show summary »

V-type ATPase V0 motor Show summary »

Transporters and Subunits

V-type ATPase V1 motor A subunit Show summary »

V-type ATPase V1 motor B1 subunit Show summary »

V-type ATPase V1 motor B2 subunit Show summary »

V-type ATPase V1 motor C1 subunit Show summary »

V-type ATPase V1 motor C2 subunit Show summary »

V-type ATPase V1 motor D subunit Show summary »

V-type ATPase V1 motor E1 subunit Show summary »

V-type ATPase V1 motor E2 subunit Show summary »

V-type ATPase V1 motor F subunit Show summary »

V-type ATPase V1 motor G1 subunit Show summary »

V-type ATPase V1 motor G2 subunit Show summary »

V-type ATPase V1 motor G3 subunit Show summary »

V-type ATPase V1 motor H subunit Show summary »

V-type ATPase V0 motor a1 subunit Show summary »

V-type ATPase V0 motor a2 subunit Show summary »

V-type ATPase V0 motor a3 subunit Show summary »

V-type ATPase V0 motor a4 subunit Show summary »

V-type ATPase V0 motor b subunit Show summary »

V-type ATPase V0 motor c subunit Show summary »

V-type ATPase V0 motor d1 subunit Show summary »

V-type ATPase V0 motor d2 subunit Show summary »

V-type ATPase V0 motor e1 subunit Show summary »

V-type ATPase V0 motor e2 subunit Show summary »

References

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How to cite this family page

Database page citation:

V-type ATPase. Accessed on 22/06/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=157.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172: 6110-6202.