Sodium-dependent HCO<sub>3</sub><sup>-</sup> transporters | Transporters

Sodium-dependent HCO₃^- transporters C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Transporters

NBCe1 (Electrogenic sodium bicarbonate cotransporter 1 / SLC4A4) C Show summary »« Hide summary

Target Id

908

Nomenclature

Electrogenic sodium bicarbonate cotransporter 1

Systematic nomenclature

SLC4A4

Common abbreviation

NBCe1

Previous and unofficial names

Genes

SLC4A4 (Hs), Slc4a4 (Mm), Slc4a4 (Rn)

Ensembl ID

ENSG00000080493 (Hs), ENSMUSG00000060961 (Mm), ENSRNOG00000003134 (Rn)

UniProtKB AC

Q9Y6R1 (Hs), O88343 (Mm), Q9JI66 (Rn)

Bioparadigms SLC Tables

SLC4A4 (Hs)

Endogenous substrates

NaHCO₃^-

Stoichiometry

1 Na⁺ : 2/3 HCO₃^- (out) or 1 Na⁺ : CO₃^2*

NBCe2 (Electrogenic sodium bicarbonate cotransporter 4 / SLC4A5) C Show summary »« Hide summary

Target Id

909

Nomenclature

Electrogenic sodium bicarbonate cotransporter 4

Systematic nomenclature

SLC4A5

Common abbreviation

NBCe2

Previous and unofficial names

NBC4 | electrogenic sodium bicarbonate cotransporter NBC4c | solute carrier family 4 member 5 | solute carrier family 4, sodium bicarbonate cotransporter, member 5 | solute carrier family 4 (sodium bicarbonate cotransporter), member 5

Genes

SLC4A5 (Hs), Slc4a5 (Mm), Slc4a5 (Rn)

Ensembl ID

ENSG00000188687 (Hs), ENSMUSG00000068323 (Mm), ENSRNOG00000010378 (Rn)

UniProtKB AC

Q9BY07 (Hs), Q6RI88 (Rn)

Bioparadigms SLC Tables

SLC4A5 (Hs)

Endogenous substrates

NaHCO₃^-

Stoichiometry

1 Na⁺ : 2/3 HCO₃^- (out) or 1 Na⁺ : CO₃^2*

NBCn1 (Electroneutral sodium bicarbonate cotransporter 1 / SLC4A7) C Show summary »« Hide summary

Target Id

910

Nomenclature

Electroneutral sodium bicarbonate cotransporter 1

Systematic nomenclature

SLC4A7

Common abbreviation

NBCn1

Previous and unofficial names

Genes

SLC4A7 (Hs), Slc4a7 (Mm), Slc4a7 (Rn)

Ensembl ID

ENSG00000033867 (Hs), ENSMUSG00000021733 (Mm), ENSRNOG00000005957 (Rn)

UniProtKB AC

Q9Y6M7 (Hs), Q8BTY2 (Mm), Q9R1N3 (Rn)

Bioparadigms SLC Tables

SLC4A7 (Hs)

Endogenous substrates

NaHCO₃^-

Stoichiometry

1 Na⁺ : 1 HCO₃^- (out) or 1 Na⁺ : CO₃^2*

NBCn2 (Electroneutral sodium bicarbonate cotransporter 2 / SLC4A10) C Show summary »« Hide summary

Target Id

911

Nomenclature

Electroneutral sodium bicarbonate cotransporter 2

Systematic nomenclature

SLC4A10

Common abbreviation

NBCn2

Previous and unofficial names

NCBE | solute carrier family 4, sodium bicarbonate transporter-like, member 10 | solute carrier family 4 member 10

Genes

SLC4A10 (Hs), Slc4a10 (Mm), Slc4a10 (Rn)

Ensembl ID

ENSG00000144290 (Hs), ENSMUSG00000026904 (Mm), ENSRNOG00000005307 (Rn)

UniProtKB AC

Q6U841 (Hs), Q5DTL9 (Mm), Q80ZA5 (Rn)

Bioparadigms SLC Tables

SLC4A10 (Hs)

Endogenous substrates

NaHCO₃^-

Stoichiometry

1 Na⁺ : 1 HCO₃^- (out) or 1 Na : CO₃^2*

NDCBE (NBCBE / SLC4A8) C Show summary »« Hide summary

Target Id

912

Nomenclature

NBCBE

Systematic nomenclature

SLC4A8

Common abbreviation

NDCBE

Previous and unofficial names

Genes

SLC4A8 (Hs), Slc4a8 (Mm), Slc4a8 (Rn)

Ensembl ID

ENSG00000050438 (Hs), ENSMUSG00000023032 (Mm), ENSRNOG00000028879 (Rn)

UniProtKB AC

Q2Y0W8 (Hs), Q8JZR6 (Mm), Q6RVG2 (Rn)

Bioparadigms SLC Tables

SLC4A8 (Hs)

Endogenous substrates

Cl^-

NaHCO₃^-

Stoichiometry

1 Na⁺ : 2HCO₃^- (in) : 1 Cl^- (out)

BTR1 (NaBC1 / SLC4A11) C Show summary »« Hide summary

Target Id

913

Nomenclature

NaBC1

Systematic nomenclature

SLC4A11

Common abbreviation

BTR1

Previous and unofficial names

Genes

SLC4A11 (Hs), Slc4a11 (Mm), Slc4a11 (Rn)

Ensembl ID

ENSG00000088836 (Hs), ENSMUSG00000074796 (Mm), ENSRNOG00000021234 (Rn)

UniProtKB AC

Q8NBS3 (Hs), A2AJN7 (Mm)

Bioparadigms SLC Tables

SLC4A11 (Hs)

Endogenous substrates

Cl^-

NaHCO₃^-

How to cite this family page

Database page citation:

Sodium-dependent HCO₃^- transporters. Accessed on 19/08/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=171.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172: 6110-6202.

Sodium-dependent HCO3- transporters C

Transporters

How to cite this family page

Sodium-dependent HCO₃^- transporters C