Neutral amino acid transporter subfamily

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Certain members of neutral amino acid transport family are expressed upon the apical surface of epithelial cells and are important for the absorption of amino acids from the duodenum, jejunum and ileum and their reabsorption within the proximal tubule of the nephron (i.e. B0AT1 (SLC6A19), SLC6A17, SLC6A18, SLC6A20). Others may function as transporters for neurotransmitters or their precursors (i.e. B0AT2, SLC6A17) [4].

Transporters

B0AT1 / SLC6A19 Show summary »

B0AT2 / SLC6A15 Show summary »

B0AT3 / SLC6A18 Show summary »

NTT5 / SLC6A16 Show summary »

NTT4 / SLC6A17 Show summary »

SIT1 / SLC6A20 Show summary »

References

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NC-IUPHAR subcommittee and family contributors

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How to cite this family page

Database page citation:

Stefan Bröer. Neutral amino acid transporter subfamily. Accessed on 23/03/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=179.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172: 6110-6202.