Mitochondrial amino acid transporter subfamily

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Mitochondrial amino acid transporters can be subdivided on the basis of their substrates. Mitochondrial ornithine transporters play a role in the urea cycle by exchanging cytosolic ornithine (L-ornithine and D-ornithine) for mitochondrial citrulline (L-citrulline and D-citrulline) in equimolar amounts. Further members of the family include transporters of S-adenosylmethionine and carnitine.

Transporters

solute carrier family 25 member 47 / SLC25A47 Show summary »

solute carrier family 25 member 48 / SLC25A48 Show summary »

AGC1 / SLC25A12 Show summary »

AGC2 / SLC25A13 Show summary »

GC2 (Mitochondrial glutamate carrier 2 / SLC25A18) Show summary »

GC1 (Mitochondrial glutamate carrier 1 / SLC25A22) Show summary »

ORC2 (Mitochondrial ornithine transporter 2 / SLC25A2) Show summary »

ORC1 (Mitochondrial ornithine transporter 1  / SLC25A15) Show summary »

CAC (Carnitine/acylcarnitine carrier / SLC25A20) Show summary »

ORNT3 / SLC25A29 Show summary »

SLC25A38 Show summary »

CGI-69 / SLC25A39 Show summary »

MCFP / SLC25A40 Show summary »

SLC25A44 Show summary »

SLC25A45 Show summary »

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References

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How to cite this family page

Database page citation:

Mitochondrial amino acid transporter subfamily. Accessed on 23/03/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=204.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172: 6110-6202.