SLC50 sugar transporter C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

« Hide

A mouse stromal cell cDNA library was used to clone C2.3 [2], later termed Rag1-activating protein 1, with a sequence homology predictive of a 4TM topology. The plant orthologues, termed SWEETs, appear to be 7 TM proteins, with extracellular N-termini, and the capacity for bidirectional flux of D-glucose [1]. Expression of mouse SWEET in the mammary gland was suggestive of a role in Golgi lactose synthesis [1].

Transporters

RAG1AP1 (SLC50 sugar exporter / SLC50A1) C Show summary »

Further reading

Show »

References

Show »

How to cite this family page

Database page citation:

SLC50 sugar transporter. Accessed on 30/04/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=336.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Transporters. Br J Pharmacol. 172: 6110-6202.