M12: Astacin/Adamalysin C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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ADAM (A Disintegrin And Metalloproteinase domain containing proteins) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

ADAMTS (with thrombospondin motifs) metalloproteinases cleave cell-surface or transmembrane proteins to generate soluble and membrane-limited products.

Enzymes

ADAM2 Show summary »

ADAM7 Show summary »

ADAM8 Show summary » More detailed page

ADAM9 Show summary » More detailed page

ADAM10 Show summary » More detailed page

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ADAM12 Show summary » More detailed page

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ADAM33 Show summary » More detailed page

ADAMTS1 Show summary » More detailed page

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ADAMTS12 Show summary »

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bone morphogenetic protein 1 Show summary » More detailed page

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How to cite this family page

Database page citation:

M12: Astacin/Adamalysin. Accessed on 21/09/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=739.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol. 172: 6024-6109.