Fatty acid-binding proteins C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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Fatty acid-binding proteins are low molecular weight (100-130 aa) chaperones for long chain fatty acids, fatty acyl CoA esters, eicosanoids, retinols, retinoic acids and related metabolites and are usually regarded as being responsible for allowing the otherwise hydrophobic ligands to be mobile in aqueous media. These binding proteins may perform functions extracellularly (e.g. in plasma) or transport these agents; to the nucleus to interact with nuclear receptors (principally PPARs and retinoic acid receptors [13]) or for interaction with metabolic enzymes. Although sequence homology is limited, crystallographic studies suggest conserved 3D structures across the group of binding proteins.

Targets

fatty acid binding protein 1 C Show summary »

fatty acid binding protein 2 C Show summary »

fatty acid binding protein 3 C Show summary » More detailed page

fatty acid binding protein 4 C Show summary » More detailed page

fatty acid binding protein 5 C Show summary »

fatty acid binding protein 6 C Show summary »

fatty acid binding protein 7 C Show summary »

peripheral myelin protein 2 C Show summary »

fatty acid binding protein 9 C Show summary »

fatty acid binding protein 12 C Show summary »

retinol binding protein 1 C Show summary »

retinol binding protein 2 C Show summary »

retinol binding protein 3 C Show summary »

retinol binding protein 4 C Show summary » More detailed page

retinol binding protein 5 C Show summary »

retinol binding protein 7 C Show summary »

retinaldehyde binding protein 1 C Show summary »

cellular retinoic acid binding protein 1 C Show summary »

cellular retinoic acid binding protein 2 C Show summary »

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References

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How to cite this family page

Database page citation:

Fatty acid-binding proteins. Accessed on 18/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=783.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Overview. Br J Pharmacol. 172: 5729-5743.