Ceramide synthase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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This family of enzymes, also known as sphingosine N-acyltransferase, is located in the ER facing the cytosol with an as-yet undefined topology and stoichiometry. Ceramide synthase in vitro is sensitive to inhibition by the fungal derived toxin, fumonisin B1.

Enzymes

CERS1 (ceramide synthase 1) C Show summary »

CERS2 (ceramide synthase 2) C Show summary »

CERS3 (ceramide synthase 3) C Show summary »

CERS4 (ceramide synthase 4) C Show summary »

CERS5 (ceramide synthase 5) C Show summary »

CERS6 (ceramide synthase 6) C Show summary »

References

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How to cite this family page

Database page citation:

Ceramide synthase. Accessed on 18/10/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=789.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Enzymes. Br J Pharmacol. 172: 6024-6109.