Ceramide synthase C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Overview

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This family of enzymes, also known as sphingosine N-acyltransferase, is located in the ER facing the cytosol with an as-yet undefined topology and stoichiometry. Ceramide synthase in vitro is sensitive to inhibition by the fungal derived toxin, fumonisin B1.

Enzymes

CERS1 (ceramide synthase 1) C Show summary »

CERS2 (ceramide synthase 2) C Show summary »

CERS3 (ceramide synthase 3) C Show summary »

CERS4 (ceramide synthase 4) C Show summary »

CERS5 (ceramide synthase 5) C Show summary »

CERS6 (ceramide synthase 6) C Show summary »

References

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How to cite this family page

Database page citation:

Ceramide synthase. Accessed on 15/12/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=789.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Kelly E, Marrion NV, Peters JA, Faccenda E, Harding SD, Pawson AJ, Sharman JL, Southan C, Davies JA; CGTP Collaborators. (2017) The Concise Guide to PHARMACOLOGY 2017/18: Enzymes. Br J Pharmacol. 174 Suppl 1: S272-S359.