Non-enzymatic BRD containing proteins C

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Bromodomains bind proteins with acetylated lysine residues, such as histones, to regulate gene transcription. Listed herein are examples of bromodomain-containing proteins for which sufficient pharmacology exists.

Targets

bromodomain adjacent to zinc finger domain 1A Show summary » More detailed page

bromodomain adjacent to zinc finger domain 1B Show summary » More detailed page

bromodomain adjacent to zinc finger domain 2A C Show summary » More detailed page

bromodomain adjacent to zinc finger domain 2B C Show summary » More detailed page

bromodomain PHD finger transcription factor Show summary » More detailed page

bromodomain testis associated Show summary » More detailed page

bromodomain and PHD finger containing 1 Show summary » More detailed page

bromodomain and PHD finger containing 3 Show summary » More detailed page

bromodomain and WD repeat domain containing 1 Show summary » More detailed page

bromodomain and WD repeat domain containing 3 Show summary » More detailed page

CECR2, histone acetyl-lysine reader Show summary » More detailed page

CREB binding protein C Show summary » More detailed page

E1A binding protein p300 Show summary » More detailed page

polybromo 1 C Show summary » More detailed page

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 Show summary » More detailed page

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 C Show summary » More detailed page

pleckstrin homology domain interacting protein Show summary » More detailed page

SP100 nuclear antigen Show summary » More detailed page

SP110 nuclear body protein Show summary » More detailed page

SP140 nuclear body protein Show summary » More detailed page

SP140 nuclear body protein like Show summary » More detailed page

zinc finger MYND-type containing 8 Show summary » More detailed page

zinc finger MYND-type containing 11 Show summary » More detailed page

tripartite motif containing 66 Show summary » More detailed page

Further reading

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References

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How to cite this family page

Database page citation:

Non-enzymatic BRD containing proteins. Accessed on 27/03/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=867.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Overview. Br J Pharmacol. 172: 5729-5743.