Other immune checkpoint proteins

Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

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Targets

CD86 C Show summary » More detailed page

CD80 C Show summary » More detailed page

CD28 Show summary » More detailed page

LAG3 (CD223) / CD223 Show summary » More detailed page

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4 (CD152)) C Show summary » More detailed page

PD-1 (programmed cell death 1 (CD279)) C Show summary » More detailed page

B7-H3 (CD276) Show summary » More detailed page

ICOS (CD278) Show summary » More detailed page

SIGLEC-2 (CD22) Show summary » More detailed page

SIGLEC-3 (CD33) C Show summary » More detailed page

TIM3 (CD366) Show summary » More detailed page

TIGIT Show summary » More detailed page

References

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How to cite this family page

Database page citation:

Other immune checkpoint proteins. Accessed on 24/11/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=949.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Kelly E, Marrion N, Peters JA, Benson HE, Faccenda E, Pawson AJ, Sharman JL, Southan C, Buneman OP, Catterall WA, Cidlowski JA, Davenport AP, Fabbro D, Fan G, McGrath JC, Spedding M, Davies JA and CGTP Collaborators (2015) The Concise Guide to PHARMACOLOGY 2015/16: Overview. Br J Pharmacol. 172: 5729-5743.