Interferons

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Overview

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Classification
Type I interferons: thirteen interferons-alpha (IFN-αs), IFN-β, IFN-κ, IFN-ω, IFN-ε, which all signal through the IFN-α/β receptor (IFNAR) that is a dimer of IFNAR1 and IFNAR2 subunits.
Type II interferon: IFN-γ which acts through the IFNGR, which comprises IFNGR1 and IFNGR2 subunits.
Type III interferons: IFN-λs which signal through a receptor complex containing IL10RB and IFNLR1.

Ligands

IFN-α1/13 {Sp: Human} Show summary » More detailed page

IFN-α2 {Sp: Human} Show summary » More detailed page

IFN-α4 {Sp: Human} Show summary » More detailed page

IFN-α5 {Sp: Human} Show summary » More detailed page

IFN-α6 {Sp: Human} Show summary » More detailed page

IFN-α7 {Sp: Human} Show summary » More detailed page

IFN-α8 {Sp: Human} Show summary » More detailed page

IFN-α10 {Sp: Human} Show summary » More detailed page

IFN-α14 {Sp: Human} Show summary » More detailed page

IFN-α16 {Sp: Human} Show summary » More detailed page

IFN-α17 {Sp: Human} Show summary » More detailed page

IFN-α21 {Sp: Human} Show summary » More detailed page

IFN-β {Sp: Human} Show summary » More detailed page

IFN-γ {Sp: Human} Show summary » More detailed page

IFN-κ {Sp: Human} Show summary » More detailed page

IFN-λ1 {Sp: Human} Show summary » More detailed page

IFN-λ2 {Sp: Human} Show summary » More detailed page

IFN-λ3 {Sp: Human} Show summary » More detailed page

IFN-ω {Sp: Human} Show summary » More detailed page

How to cite this family page

Database page citation:

Interferons. Accessed on 25/11/2017. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=957.