G protein-coupled receptors

Download information on GPCRs as part of our target list in CSV format

Class Frizzled GPCRs
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
Class Frizzled GPCRs Wnt-1 {Sp: Human}
Wnt-2 {Sp: Human}
Wnt-5a {Sp: Human}
Wnt-3a {Sp: Human}
Wnt-7b {Sp: Human}
FZD1 FZD1
Fzd1
Fzd1
Class Frizzled GPCRs Wnt-5a {Sp: Human}
FZD2 FZD2
Fzd2
Fzd2
Class Frizzled GPCRs FZD3 FZD3
Fzd3
Fzd3
The is some evidence for Wnt-5a and Wnt-3 binding to the receptor
Class Frizzled GPCRs Wnt FZD4 FZD4
Fzd4
Fzd4
Class Frizzled GPCRs WNTs FZD5 FZD5
Fzd5
Fzd5
Class Frizzled GPCRs Wnt-4 {Sp: Human}
Wnt-5a {Sp: Human}
Wnt-3a {Sp: Human}
FZD6 FZD6
Fzd6
Fzd6
Class Frizzled GPCRs Wnt FZD7 FZD7
Fzd7
Fzd7
Class Frizzled GPCRs Wnt FZD8 FZD8
Fzd8
Fzd8
Class Frizzled GPCRs Wnt FZD9 FZD9
Fzd9
Fzd9
Class Frizzled GPCRs Wnt FZD10 FZD10
Fzd10
Class Frizzled GPCRs constitutive SMO SMO
Smo
Smo