Ion channel subunits

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5-HT3 receptors
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
5-HT3 receptors 5-hydroxytryptamine
5-HT3A HTR3A
Htr3a
Htr3a
5-HT3 receptors 5-hydroxytryptamine
5-HT3B HTR3B
Htr3b
Htr3b
5-HT3 receptors 5-hydroxytryptamine
5-HT3C HTR3C
5-HT3 receptors 5-hydroxytryptamine
5-HT3D HTR3D
5-HT3 receptors 5-hydroxytryptamine
5-HT3E HTR3E
5-HT3 receptors 5-hydroxytryptamine
5-HT3AB
5-HT3 receptors 5-hydroxytryptamine
5-HT3A
Acid-sensing (proton-gated) ion channels (ASICs)
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
Acid-sensing (proton-gated) ion channels (ASICs) H+
ASIC1 ASIC1
Asic1
Asic1
Acid-sensing (proton-gated) ion channels (ASICs) H+
ASIC2 ASIC2
Asic2
Asic2
Acid-sensing (proton-gated) ion channels (ASICs) H+
ASIC3 ASIC3
Asic3
Asic3
Epithelial sodium channels (ENaC)
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
Epithelial sodium channels (ENaC) sodium ENaC α SCNN1A
Scnn1a
Scnn1a
Epithelial sodium channels (ENaC) sodium ENaC β SCNN1B
Scnn1b
Scnn1b
Epithelial sodium channels (ENaC) sodium ENaC δ SCNN1D
Epithelial sodium channels (ENaC) sodium ENaC γ SCNN1G
Scnn1g
Scnn1g
Epithelial sodium channels (ENaC) sodium ENaCαβγ
GABAA receptors
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
GABAA receptors GABA
GABAA receptor α1 subunit GABRA1
Gabra1
Gabra1
GABAA receptors GABA
GABAA receptor α2 subunit GABRA2
Gabra2
Gabra2
GABAA receptors GABA
GABAA receptor α3 subunit GABRA3
Gabra3
Gabra3
GABAA receptors GABA
GABAA receptor α4 subunit GABRA4
Gabra4
Gabra4
GABAA receptors GABA
GABAA receptor α5 subunit GABRA5
Gabra5
Gabra5
GABAA receptors GABA
GABAA receptor α6 subunit GABRA6
Gabra6
Gabra6
GABAA receptors GABA
GABAA receptor β1 subunit GABRB1
Gabrb1
Gabrb1
GABAA receptors GABA
GABAA receptor β2 subunit GABRB2
Gabrb2
Gabrb2
GABAA receptors GABA
GABAA receptor β3 subunit GABRB3
Gabrb3
Gabrb3
GABAA receptors GABA
GABAA receptor γ1 subunit GABRG1
Gabrg1
Gabrg1
GABAA receptors GABA
GABAA receptor γ2 subunit GABRG2
Gabrg2
Gabrg2
GABAA receptors GABA
GABAA receptor γ3 subunit GABRG3
Gabrg3
Gabrg3
GABAA receptors GABA
GABAA receptor δ subunit GABRD
Gabrd
Gabrd
GABAA receptors GABA
GABAA receptor ε subunit GABRE
Gabre
Gabre
GABAA receptors GABA
GABAA receptor θ subunit GABRQ
Gabrq
Gabrq
GABAA receptors GABA
GABAA receptor π subunit GABRP
Gabrp
Gabrp
GABAA receptors GABA
GABAA receptor ρ1 subunit GABRR1
Gabrr1
Gabrr1
GABAA receptors GABA
GABAA receptor ρ2 subunit GABRR2
Gabrr2
Gabrr2
GABAA receptors GABA
GABAA receptor ρ3 subunit GABRR3
Gabrr3
Gabrr3
Glycine receptors
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
Glycine receptors glycine
glycine receptor α1 subunit GLRA1
Glra1
Glra1
Glycine receptors glycine
glycine receptor α2 subunit GLRA2
Glra2
Glra2
Glycine receptors glycine
glycine receptor α3 subunit GLRA3
Glra3
Glra3
Glycine receptors glycine
glycine receptor α4 subunit (pseudogene in humans) GLRA4
Glra4
Glra4
Glycine receptors glycine
glycine receptor β subunit GLRB
Glrb
Glrb
Glycine receptors glycine
Glycine Receptor (All subtypes)
Ionotropic glutamate receptors
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
Ionotropic glutamate receptors L-glutamic acid
GluA1 GRIA1
Gria1
Gria1
Ionotropic glutamate receptors L-glutamic acid
GluA2 GRIA2
Gria2
Gria2
Ionotropic glutamate receptors L-glutamic acid
GluA3 GRIA3
Gria3
Gria3
Ionotropic glutamate receptors L-glutamic acid
GluA4 GRIA4
Gria4
Gria4
Ionotropic glutamate receptors L-glutamic acid
GluD1 GRID1
Grid1
Grid1
Ionotropic glutamate receptors L-glutamic acid
GluD2 GRID2
Grid2
Grid2
Ionotropic glutamate receptors L-glutamic acid
GluK1 GRIK1
Grik1
Grik1
Ionotropic glutamate receptors L-glutamic acid
GluK2 GRIK2
Grik2
Grik2
Ionotropic glutamate receptors L-glutamic acid
GluK3 GRIK3
Grik3
Grik3
Ionotropic glutamate receptors L-glutamic acid
GluK4 GRIK4
Grik4
Grik4
Ionotropic glutamate receptors L-glutamic acid
GluK5 GRIK5
Grik5
Grik5
Ionotropic glutamate receptors L-glutamic acid
GluN1 GRIN1
Grin1
Grin1
Ionotropic glutamate receptors L-glutamic acid
GluN2A GRIN2A
Grin2a
Grin2a
Ionotropic glutamate receptors L-glutamic acid
GluN2B GRIN2B
Grin2b
Grin2b
Ionotropic glutamate receptors L-glutamic acid
GluN2C GRIN2C
Grin2c
Grin2c
Ionotropic glutamate receptors L-glutamic acid
GluN2D GRIN2D
Grin2d
Grin2d
Ionotropic glutamate receptors L-glutamic acid
GluN3A GRIN3A
Grin3a
Grin3a
Ionotropic glutamate receptors L-glutamic acid
GluN3B GRIN3B
Grin3b
Grin3b
IP3 receptor
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
IP3 receptor IP3
IP3R1 ITPR1
Itpr1
Itpr1
IP3 receptor IP3
IP3R2 ITPR2
Itpr2
Itpr2
IP3 receptor IP3
IP3R3 ITPR3
Itpr3
Itpr3
Nicotinic acetylcholine receptors
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α1 subunit CHRNA1
Chrna1
Chrna1
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α2 subunit CHRNA2
Chrna2
Chrna2
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α3 subunit CHRNA3
Chrna3
Chrna3
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α4 subunit CHRNA4
Chrna4
Chrna4
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α5 subunit CHRNA5
Chrna5
Chrna5
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α6 subunit CHRNA6
Chrna6
Chrna6
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α7 subunit CHRNA7
Chrna7
Chrna7
Nicotinic acetylcholine receptors nicotinic acetylcholine receptor α8 subunit (avian)
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α9 subunit CHRNA9
Chrna9
Chrna9
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor α10 subunit CHRNA10
Chrna10
Chrna10
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor β1 subunit CHRNB1
Chrnb1
Chrnb1
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor β2 subunit CHRNB2
Chrnb2
Chrnb2
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor β3 subunit CHRNB3
Chrnb3
Chrnb3
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor β4 subunit CHRNB4
Chrnb4
Chrnb4
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor γ subunit CHRNG
Chrng
Chrng
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor δ subunit CHRND
Chrnd
Chrnd
Nicotinic acetylcholine receptors acetylcholine
nicotinic acetylcholine receptor ε subunit CHRNE
Chrne
Chrne
P2X receptors
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
P2X receptors ATP
P2X1 P2RX1
P2rx1
P2rx1
P2X receptors ATP
P2X2 P2RX2
P2rx2
P2rx2
P2X receptors ATP
P2X3 P2RX3
P2rx3
P2rx3
P2X receptors ATP
P2X4 P2RX4
P2rx4
P2rx4
P2X receptors ATP
P2X5 P2RX5
P2rx5
P2rx5
P2X receptors ATP
P2X6 P2RX6
P2rx6
P2rx6
P2X receptors ATP
P2X7 P2RX7
P2rx7
P2rx7
ZAC
Family name Ligand Official IUPHAR receptor name Human gene symbol Rat gene symbol Mouse gene symbol Comment
ZAC Zn2+
ZAC ZACN