Ligand id: 1135

Name: exendin-4

Compound class Peptide or derivative
Approved drug? Yes (FDA (2005), EMA (2006))
International Nonproprietary Names
INN number INN
8219 exenatide
AC 2993 | AC002993 | AC2993A | Bydureon® | Byetta®
Database Links
BindingDB Ligand 50241203
CAS Registry No. 141758-74-9 (source: Scifinder)
ChEMBL Ligand CHEMBL414357
DrugBank Ligand DB01276
PubChem CID 16157882
Search PubMed clinical trials exenatide
Search PubMed titles exenatide
Search PubMed titles/abstracts exenatide
UniProtKB P26349 (Hsu)
Wikipedia Exenatide
This peptide is found in the venom of the Gila monster Heloderma suspectum. Exenatide is the synthetic form of the peptide. This peptide sequence is a GLP-1 analogue [1]. The is some ambiguity surrounding the exact stereochemistry of exendin-4, but for represetations of the chemical structure of the peptide, please see the PubChem, ChEMBL and ChEBI entries linked to above.