erythromycin-A

Ligand id: 1456

Name: erythromycin-A

Abbreviated name: EM-A

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 14
Hydrogen bond donors 5
Rotatable bonds 7
Topological polar surface area 193.91
Molecular weight 733.46
XLogP 1.14
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
Approved drug? Yes (source: FDA (no history prior to 1964))
IUPAC Name
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
International Nonproprietary Names
INN number INN
39 erythromycin
Synonyms
E-Mycin®
Erythrocin®
erythromycin
Database Links
BindingDB Ligand 50344942
BitterDB Ligand 99
CAS Registry No. 114-07-8 (source: ChEBI)
ChEBI CHEBI:42355
ChEMBL Ligand CHEMBL532
DrugBank Ligand DB00199
PharmGKB Drug PA449493
PubChem CID 12560
RCSB PDB Ligand ERY
Search Google for chemical match using the InChIKey ULGZDMOVFRHVEP-RWJQBGPGSA-N
Search Google for chemicals with the same backbone ULGZDMOVFRHVEP
Search PubMed clinical trials erythromycin
Search PubMed titles erythromycin
Search PubMed titles/abstracts erythromycin
Wikipedia Erythromycin
Comments
Erythromycin is a macrolide antibiotic produced by Streptomyces erythreus