perphenazine

Ligand id: 209

Name: perphenazine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: perphenazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 55.25
Molecular weight 403.15
XLogP 3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1957))
IUPAC Name
2-[4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
International Nonproprietary Names
INN number INN
637 perphenazine
Synonyms
Decentan® | Fentazin® | Trilafon®
Database Links
BindingDB Ligand 50130273
CAS Registry No. 58-39-9
ChEBI CHEBI:8028
ChEMBL Ligand CHEMBL567
DrugBank Ligand DB00850
PubChem CID 4748
Search Google for chemical match using the InChIKey RGCVKNLCSQQDEP-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RGCVKNLCSQQDEP
Search PubMed clinical trials perphenazine
Search PubMed titles perphenazine
Search PubMed titles/abstracts perphenazine
Search UniChem for chemical match using the InChIKey RGCVKNLCSQQDEP-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RGCVKNLCSQQDEP
Wikipedia Perphenazine
Comments
Perphenazine is a typical antipsychotic drug, acting principally as a dopamine D2 receptor antagonist.