dihydrotestosterone

Ligand id: 2856

Name: dihydrotestosterone

Abbreviated name: DHT

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 37.3
Molecular weight 290.22
XLogP 4.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
IUPAC Name
(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
238 androstanolone
Synonyms
5α-dihydrotestosterone | androstanolone | stanolone
Comments
Dihydrotestosterone is an androgenic metabolite of testosterone, it is the primary contributing factor in male pattern baldness.
Database Links
BindingDB Ligand 18161
CAS Registry No. 521-18-6 (source: Scifinder)
ChEBI CHEBI:16330
ChEMBL Ligand CHEMBL27769
DrugBank Ligand DB02901
GtoPdb PubChem SID 135651474
NURSA Ligand 10.1621/1VFECP1A76
PubChem CID 10635
RCSB PDB Ligand DHT
Search Google for chemical match using the InChIKey NVKAWKQGWWIWPM-ABEVXSGRSA-N
Search Google for chemicals with the same backbone NVKAWKQGWWIWPM
Search PubMed clinical trials androstanolone
Search PubMed titles androstanolone
Search PubMed titles/abstracts androstanolone
Search UniChem for chemical match using the InChIKey NVKAWKQGWWIWPM-ABEVXSGRSA-N
Search UniChem for chemicals with the same backbone NVKAWKQGWWIWPM
SynPHARM 6559 (in complex with Androgen receptor)
14316 (in complex with Androgen receptor)
Wikipedia Dihydrotestosterone