dihydrotestosterone

Ligand id: 2856

Name: dihydrotestosterone

Abbreviated name: DHT

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Topological polar surface area 37.3
Molecular weight 290.22
XLogP 4.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
IUPAC Name
(5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
International Nonproprietary Names
INN number INN
238 androstanolone
Synonyms
5α-dihydrotestosterone | androstanolone | stanolone
Database Links
BindingDB Ligand 18161
CAS Registry No. 521-18-6 (source: Scifinder)
ChEBI CHEBI:16330
ChEMBL Ligand CHEMBL27769
DrugBank Ligand DB02901
GtoPdb PubChem SID 135651474
NURSA Ligand 10.1621/1VFECP1A76
PubChem CID 10635
RCSB PDB Ligand DHT
Search Google for chemical match using the InChIKey NVKAWKQGWWIWPM-ABEVXSGRSA-N
Search Google for chemicals with the same backbone NVKAWKQGWWIWPM
Search PubMed clinical trials androstanolone
Search PubMed titles androstanolone
Search PubMed titles/abstracts androstanolone
Search UniChem for chemical match using the InChIKey NVKAWKQGWWIWPM-ABEVXSGRSA-N
Search UniChem for chemicals with the same backbone NVKAWKQGWWIWPM
SynPHARM 6559 (in complex with Androgen receptor)
14316 (in complex with Androgen receptor)
Wikipedia Dihydrotestosterone
Comments
Dihydrotestosterone is an androgenic metabolite of testosterone, it is the primary contributing factor in male pattern baldness.