clomiphene

Ligand id: 4159

Name: clomiphene

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 0
Rotatable bonds 9
Topological polar surface area 12.47
Molecular weight 405.19
XLogP 9.85
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1967))
IUPAC Name
{2-[4-(2-chloro-1,2-diphenylethenyl)phenoxy]ethyl}diethylamine
International Nonproprietary Names
INN number INN
1309 clomifene
Synonyms
Androxal® | Clomid® | clomifene | MER-41 | MRL-41 | Omifin® | RMI-16289
Database Links
CAS Registry No. 911-45-5 (source: Scifinder)
ChEBI CHEBI:3752
ChEMBL Ligand CHEMBL2355051
DrugBank Ligand DB00882
GtoPdb PubChem SID 178100979
PubChem CID 2800
Search Google for chemical match using the InChIKey GKIRPKYJQBWNGO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GKIRPKYJQBWNGO
Search PubMed clinical trials clomifene
Search PubMed titles clomifene
Search PubMed titles/abstracts clomifene
Search UniChem for chemical match using the InChIKey GKIRPKYJQBWNGO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GKIRPKYJQBWNGO
Wikipedia Clomifene
Comments
Clomiphene is an estrogen receptor alpha modulator, it can act an agonist or antagonist depending on the target tissue. The approved drug clomiphene is a racemic mixture of the two geometric isomers, E and Z clomiphene (also known as enclomiphene and zuclomiphene). Zuclomifene is the more active isomer.