cytarabine

Ligand id: 4827

Name: cytarabine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 5
Rotatable bonds 2
Topological polar surface area 128.28
Molecular weight 244.09
XLogP -1.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1969), EMA (2001))
IUPAC Name
4-amino-1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2-dihydropyrimidin-2-one
International Nonproprietary Names
INN number INN
1709 cytarabine
Synonyms
Cytosar® | DepoCyte® | U-19920
Database Links
CAS Registry No. 147-94-4 (source: Scifinder)
ChEMBL Ligand CHEMBL803
DrugBank Ligand DB00987
GtoPdb PubChem SID 178101529
PubChem CID 6253
RCSB PDB Ligand AR3
Search Google for chemical match using the InChIKey UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Search Google for chemicals with the same backbone UHDGCWIWMRVCDJ
Search PubMed clinical trials cytarabine
Search PubMed titles cytarabine
Search PubMed titles/abstracts cytarabine
Search UniChem for chemical match using the InChIKey UHDGCWIWMRVCDJ-CCXZUQQUSA-N
Search UniChem for chemicals with the same backbone UHDGCWIWMRVCDJ
Wikipedia Cytarabine
Comments
Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA.