AG1478

Ligand id: 4862

Name: AG1478

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 56.27
Molecular weight 315.08
XLogP 3.29
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
Synonyms
AG 1478
AG-1478
tyrphostin AG1478
Database Links
CAS Registry No. 175178-82-2 (source: ChemSpider)
ChEMBL Ligand CHEMBL7917
PubChem CID 2051
RCSB PDB Ligand 0TO
Search Google for chemical match using the InChIKey GFNNBHLJANVSQV-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GFNNBHLJANVSQV
Comments
Tyrphostin AG 1478 is a selective inhibitor of the EGFR tyrosine kinase. It is compound 4 in [3].