BMP-15

Ligand id: 4880

Name: BMP-15

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Bone morphogenetic proteins
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
BMP15 bone morphogenetic protein 15 Human prepro-bone morphogenetic protein 15 GDF9B
Synonyms
GDF-9B | growth/differentiation factor 9B
Database Links
CATH/Gene3D 2.10.90.10
Ensembl Gene ENSG00000130385 (Hs)
Human Protein Atlas ENSG00000130385 (Hs)
UniProtKB O95972 (Hs)
Wikipedia BMP15
Comments
The BMP-15 gene is X-linked and expressed in oocytes. BMP-15 protein appears to be involved in early ovarian folliculogenesis [1-3], acting in synergy with growth/differentiation factor-9 [4]. BMP-15 is a selective modulator of FSH action [3]. The active peptide is a disulphide bond-linked homodimer.