anastrozole

Ligand id: 5137

Name: anastrozole

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 78.29
Molecular weight 293.16
XLogP 1.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1995))
IUPAC Name
2-[3-(1-cyano-1-methylethyl)-5-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
International Nonproprietary Names
INN number INN
7274 anastrozole
Synonyms
Arimidex®
Database Links
CAS Registry No. 120511-73-1
ChEMBL Ligand CHEMBL1399
DrugBank Ligand DB01217
PubChem CID 2187
Search Google for chemical match using the InChIKey YBBLVLTVTVSKRW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone YBBLVLTVTVSKRW
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Wikipedia Anastrazole
Comments
Anastrozole decreases the amount of estrogens that the body makes by inhibiting the enzyme aromatase, which is responsible for converting androgens to estrogens in females.