PF-04418948

Ligand id: 5817

Name: PF-04418948

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 76.07
Molecular weight 409.13
XLogP 3.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
1-(4-fluorobenzoyl)-3-[(6-methoxynaphthalen-2-yl)oxymethyl]azetidine-3-carboxylic acid
Synonyms
PF 04418948 | PF04418948
Database Links
CAS Registry No. 1078166-57-0 (source: Scifinder)
ChEMBL Ligand CHEMBL3286797
PubChem CID 25114442
Search Google for chemical match using the InChIKey LWJGMYMNSNVCEM-UHFFFAOYSA-N
Search Google for chemicals with the same backbone LWJGMYMNSNVCEM
Search UniChem for chemical match using the InChIKey LWJGMYMNSNVCEM-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone LWJGMYMNSNVCEM
Comments
PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist [1]. PF-04418948 was investigated in Phase I clinical trial, following which development was discontinued.