candesartan

Ligand id: 587

Name: candesartan

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 118.81
Molecular weight 440.16
XLogP 6.89
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1998))
Prodrug candesartan cilexetil
IUPAC Name
2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
International Nonproprietary Names
INN number INN
7239 candesartan
Synonyms
CV-11974 | TCV-116 (prodrug)
Database Links
BindingDB Ligand 50240609
CAS Registry No. 139481-59-7 (source: DrugBank)
ChEBI CHEBI:3347
ChEMBL Ligand CHEMBL1016
DrugBank Ligand DB00796
PubChem CID 2541
Search Google for chemical match using the InChIKey HTQMVQVXFRQIKW-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HTQMVQVXFRQIKW
Search PubMed clinical trials candesartan
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Search UniChem for chemical match using the InChIKey HTQMVQVXFRQIKW-UHFFFAOYSA-N
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Wikipedia Candesartan
Comments
Candesartan is an angiotensin II receptor antagonist. The compound is administered as the prodrug candesartan cilexetil (Atacand®).