alogliptin

Ligand id: 6319

Name: alogliptin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 93.67
Molecular weight 339.17
XLogP 1.32
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2013))
IUPAC Name
2-({6-[(3R)-3-aminopiperidin-1-yl]-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl}methyl)benzonitrile
International Nonproprietary Names
INN number INN
8814 alogliptin
Synonyms
Nesina® | SYR-322 | Vipidia®
Database Links
CAS Registry No. 850649-61-5 (source: Scifinder)
ChEMBL Ligand CHEMBL376359
DrugBank Ligand DB06203
PubChem CID 11450633
RCSB PDB Ligand T22
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SynPHARM 78493 (in complex with dipeptidyl peptidase 4)
Wikipedia Alogliptin
Comments
Alogliptin is a once-daily, oral dipeptidyl peptidase-4 (DPP-4) inhibitor class anti-diabetic drug.