abciximab

Ligand id: 6584

Name: abciximab

Classification
Compound class Antibody
Approved drug? Yes (source: FDA (1994))
International Nonproprietary Names
INN number INN
7200 abciximab
Synonyms
7E3 antibody
antiGPIIBIIIa
C7E3
ReoPro®
Database Links
Specialist databases
IMGT/mAb-DB 146
Other databases
PubChem SID 178103197
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Wikipedia Abciximab
Comments
Abciximab is a chimeric human-murine monoclonal antibody Fab (fragment antigen binding) fragment designed to target glycoprotein IIb/IIIa receptor, a key mediator of platelet aggregation and clot formation [2]. The invention of abciximab is covered by patent US5976532 [1], where its originating antibody is coded c7E3.