adrenomedullin

Ligand id: 683

Name: adrenomedullin

Abbreviated name: AM

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Neuropeptides
Comments
Adrenomedullin is 52 amino acid peptide which is mainly expressed in endothelial and smooth muscle cells. It acts as a vasodilatory peptide and it is known to regulate endothelial barrier function and vascular tone. Evidence from animal models indicates that it is a key player in the development of sepsis-associated hemodynamic and microcirculatory disorders.
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
ADM adrenomedullin Human prepro-adrenomedullin AM
Database Links
CAS Registry No. 148498-78-6 (Hs)
Ensembl Gene ENSG00000148926 (Hs)
Entrez Gene 133 (Hs)
GtoPdb PubChem SID 135651602
Human Protein Atlas ENSG00000148926 (Hs)
UniProtKB P35318 (Hs)
Wikipedia Adrenomedullin