amlodipine

Ligand id: 6981

Name: amlodipine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 99.88
Molecular weight 408.15
XLogP 3.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1992))
IUPAC Name
O3-ethyl O5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
International Nonproprietary Names
INN number INN
5729 amlodipine
Synonyms
amlodipine besylate
amlodipine maleate
Norvasc®
UK-4834011
Database Links
CAS Registry No. 88150-42-9 (source: Scifinder)
ChEMBL Ligand CHEMBL1491
DrugBank Ligand DB00381
PubChem CID 2162
Search Google for chemical match using the InChIKey HTIQEAQVCYTUBX-UHFFFAOYSA-N
Search Google for chemicals with the same backbone HTIQEAQVCYTUBX
Search PubMed clinical trials amlodipine
Search PubMed titles amlodipine
Search PubMed titles/abstracts amlodipine
Wikipedia Amlodipine
Comments
Amlodipine is a long-acting dihydropyridine class calcium channel blocker. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).