fluticasone propionate

Ligand id: 7080

Name: fluticasone propionate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 105.97
Molecular weight 500.18
XLogP 3.39
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Metabolite or derivative
Approved drug? Yes (source: FDA (1996))
IUPAC Name
[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
International Nonproprietary Names
INN number INN
5636 fluticasone
Synonyms
Advair Diskus®
ArmonAir RespiClickTM
CCI-18781
Flovent®
Database Links
CAS Registry No. 80474-14-2
ChEMBL Ligand CHEMBL1473
DrugBank Ligand DB00588
PubChem CID 444036
Search Google for chemical match using the InChIKey WMWTYOKRWGGJOA-CENSZEJFSA-N
Search Google for chemicals with the same backbone WMWTYOKRWGGJOA
Search PubMed clinical trials fluticasone
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Wikipedia Fluticasone propionate
Comments
Fluticasone propionate is a corticosteroid, high affinity and selective glucocorticoid receptor agonist.