mitomycin C

Ligand id: 7089

Name: mitomycin C

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 4
Topological polar surface area 147.88
Molecular weight 334.13
XLogP -0.25
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
Approved drug? Yes (source: FDA (1981))
International Nonproprietary Names
INN number INN
3043 mitomycin
Synonyms
Mitosol® | NSC-26980
Database Links
CAS Registry No. 1404-00-8 (source: Scifinder)
ChEBI CHEBI:27504
ChEMBL Ligand CHEMBL105
DrugBank Ligand DB00305
PubChem CID 5746
Search Google for chemical match using the InChIKey NWIBSHFKIJFRCO-WUDYKRTCSA-N
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Search PubMed clinical trials mitomycin
Search PubMed titles mitomycin
Search PubMed titles/abstracts mitomycin
Search UniChem for chemical match using the InChIKey NWIBSHFKIJFRCO-WUDYKRTCSA-N
Search UniChem for chemicals with the same backbone NWIBSHFKIJFRCO
Comments
Mitomycin C is an antineoplastic drug, with DNA alkylating activity. It is one of the mitomycin family of compounds, isolated from Streptomyces caespitosus or Streptomyces lavendulae.