rescinnamine

Ligand id: 7098

Name: rescinnamine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 1
Rotatable bonds 11
Topological polar surface area 117.78
Molecular weight 634.29
XLogP 3.39
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Natural product or derivative
Approved drug? Yes
IUPAC Name
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-[(E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoyl]oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
International Nonproprietary Names
INN number INN
683 rescinnamine
Comments
Rescinnamine is an angiotensin-converting enzyme (ACE) inhibitor. There is no information regarding approval for clinical use of this drug on the US FDA website. Other national approval agencies may have granted marketing authorisation.
Database Links
CAS Registry No. 24815-24-5
ChEBI CHEBI:28572
ChEMBL Ligand CHEMBL1668
DrugBank Ligand DB01180
GtoPdb PubChem SID 178103676
PubChem CID 5280954
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Wikipedia Rescinnamine