bisoprolol

Ligand id: 7129

Name: bisoprolol

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: bisoprolol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 12
Topological polar surface area 59.95
Molecular weight 325.23
XLogP 2.37
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1992))
IUPAC Name
[2-hydroxy-3-(4-{[2-(propan-2-yloxy)ethoxy]methyl}phenoxy)propyl](propan-2-yl)amine
International Nonproprietary Names
INN number INN
5225 bisoprolol
Synonyms
CL-297939 | EMD-33512 | Zebeta®
Database Links
CAS Registry No. 66722-44-9
ChEMBL Ligand CHEMBL645
DrugBank Ligand DB00612
PubChem CID 2405
Search Google for chemical match using the InChIKey VHYCDWMUTMEGQY-UHFFFAOYSA-N
Search Google for chemicals with the same backbone VHYCDWMUTMEGQY
Search PubMed clinical trials bisoprolol
Search PubMed titles bisoprolol
Search PubMed titles/abstracts bisoprolol
Search UniChem for chemical match using the InChIKey VHYCDWMUTMEGQY-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone VHYCDWMUTMEGQY
Wikipedia Bisoprolol
Comments
Bisoprolol is a β-blocker, selective for β1-adrenoceptors in cardiac tissue. The S(-) enantiomer is believed to account for most of its β-blocking activity.
Marketed formulations may contain bisoprolol fumarate (PubChem CID 6917733).