chlorthalidone

Ligand id: 7147

Name: chlorthalidone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 121.36
Molecular weight 338.01
XLogP 1.82
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1960), UK (1998))
IUPAC Name
2-chloro-5-(1,3-dihydroxy-1H-isoindol-1-yl)benzene-1-sulfonamide
International Nonproprietary Names
INN number INN
1125 chlortalidone
Synonyms
G-33182
Hygroton®
Database Links
CAS Registry No. 77-36-1
ChEMBL Ligand CHEMBL1055
DrugBank Ligand DB00310
PubChem CID 2732
Search Google for chemical match using the InChIKey JIVPVXMEBJLZRO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JIVPVXMEBJLZRO
Search PubMed clinical trials chlortalidone
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Search PubMed titles/abstracts chlortalidone
Wikipedia Chlortalidone
Comments
Chlorthalidone is a thiazide-like diuretic. It has a longer duration of action than other thiazide drugs.