cyclizine

Ligand id: 7151

Name: cyclizine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 6.48
Molecular weight 266.18
XLogP 5.56
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (date unknown))
IUPAC Name
1-(diphenylmethyl)-4-methylpiperazine
International Nonproprietary Names
INN number INN
176 cyclizine
Synonyms
Marezine®
Database Links
CAS Registry No. 82-92-8
ChEMBL Ligand CHEMBL648
DrugBank Ligand DB01176
PubChem CID 6726
Search Google for chemical match using the InChIKey UVKZSORBKUEBAZ-UHFFFAOYSA-N
Search Google for chemicals with the same backbone UVKZSORBKUEBAZ
Search PubMed clinical trials cyclizine
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Wikipedia Cyclizine
Comments
Cyclizine is an antihistamine drug used primarily for its anti-nausea and antiemetic actions. It is on the World Health Organization's List of Essential Medicines (link to 2015 list).