flutemetamol

Ligand id: 7342

Name: flutemetamol    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 73.39
Molecular weight 274.06
XLogP 2.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2013))
IUPAC Name
2-[3-(18F)fluoro-4-(methylamino)phenyl]-1,3-benzothiazol-6-ol
International Nonproprietary Names
INN number INN
9169 flutemetamol (18F)
Synonyms
18F-flutemetamol | [18F]flutemetamol | flutemetamol F18
Database Links
CAS Registry No. 765922-62-1 (source: SciFinder)
ChEMBL Ligand CHEMBL2042122
PubChem CID 15950376
Search Google for chemical match using the InChIKey VVECGOCJFKTUAX-HUYCHCPVSA-N
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Search UniChem for chemical match using the InChIKey VVECGOCJFKTUAX-HUYCHCPVSA-N
Search UniChem for chemicals with the same backbone VVECGOCJFKTUAX
Wikipedia Flutemetamol (18F)
Comments
Flutemetamol F-18 (Vizamyl GE Healthcare) is a positron emission tomography (PET) radiotracer approved in 2013 that binds to amyloid plaques in Alzheimer's disease neurodegeneration. However imaging agents have been granted only narrow approval since they can not be used to definitively diagnose Alzheimer's disease or to gauge treatment effectiveness, only to support other diagnostic criteria [2].