alvimopan

Ligand id: 7471

Name: alvimopan

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 89.87
Molecular weight 424.24
XLogP 5.71
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (2008))
IUPAC Name
2-[[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]methyl]-3-phenylpropanoyl]amino]acetic acid
International Nonproprietary Names
INN number INN
8245 alvimopan
Synonyms
ADL 8-2698 | Entereg®
Database Links
CAS Registry No. 156053-89-3
ChEMBL Ligand CHEMBL270190
DrugBank Ligand DB06274
PubChem CID 5488548
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Wikipedia Alvimopan
Comments
Alvimopan is a peripherally acting mu-opioid receptor antagonist , or PAMORA.