belinostat

Ligand id: 7496

Name: belinostat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 6
Topological polar surface area 103.88
Molecular weight 318.07
XLogP 3.22
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2014))
IUPAC Name
(E)-N-hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
International Nonproprietary Names
INN number INN
8823 belinostat
Synonyms
Beleodaq®
PXD-101
PXD101
Database Links
CAS Registry No. 414864-00-9
ChEBI CHEBI:61076
ChEMBL Ligand CHEMBL408513
DrugBank Ligand DB05015
PubChem CID 6918638
RCSB PDB Ligand 5OG
Search Google for chemical match using the InChIKey NCNRHFGMJRPRSK-MDZDMXLPSA-N
Search Google for chemicals with the same backbone NCNRHFGMJRPRSK
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Wikipedia Belinostat
Comments
Belinostat is a pan-histone deacetylase (HDAC) inhibitor [1,3].