perospirone

Ligand id: 7556

Name: perospirone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 84.99
Molecular weight 426.21
XLogP 3.23
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
(3aS,7aR)-2-[4-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]butyl]-3a,4,5,6,7,7a-hexahydroisoindole-1,3-dione
Synonyms
Lullan® (Japan)
Comments
Perospirone is an azapirone class atypical (second generation) antipsychotic. A higher incidence of extrapyramidal side-effects is associated with perospirone use than with other atypical antipsychotics, but fewer than reported with typical (first generation) antipsychotics.
Database Links
ChEMBL Ligand CHEMBL1472975
GtoPdb PubChem SID 223365892
PubChem CID 115368
Search Google for chemical match using the InChIKey FBVFZWUMDDXLLG-HDICACEKSA-N
Search Google for chemicals with the same backbone FBVFZWUMDDXLLG
Search UniChem for chemical match using the InChIKey FBVFZWUMDDXLLG-HDICACEKSA-N
Search UniChem for chemicals with the same backbone FBVFZWUMDDXLLG
Wikipedia Perospirone