amfenac

Ligand id: 7565

Name: amfenac

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 80.39
Molecular weight 255.09
XLogP 3.88
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
Prodrug nepafenac
IUPAC Name
2-[2-amino-3-(benzoyl)phenyl]acetic acid
International Nonproprietary Names
INN number INN
4363 amfenac
Synonyms
AHR-5850D | Fenazox® (Japan)
Database Links
CAS Registry No. 51579-82-9
ChEBI CHEBI:75915
ChEMBL Ligand CHEMBL25146
PubChem CID 2136
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Wikipedia Amfenac
Comments
Amfenac is the active metabolite of nepafenac. It is a potent non-steroidal antiinflammatory drug (NSAID) [2].
Marketed formulations may contain amfenac sodium (PubChem CID 23665728).