Ligand id: 758

Name: CCL5

Species: Human

Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Gene symbol Gene name Species Precursor protein name Synonyms
CCL5 C-C motif chemokine ligand 5 Human chemokine (C-C motif) ligand 5 beta-chemokine RANTES, chemokine (C-C motif) ligand 5, D17S136E, MGC17164, RANTES, regulated upon activation, normally T-expressed, and presumably secreted, SCYA5, SISd, SIS-delta, small inducible cytokine A5 (RANTES), small inducible cytokine subfamily A (Cys-Cys), member 5, T-cell specific protein p288, T-cell specific RANTES protein, TCP228
eosinophil chemotactic cytokine [EoCP] | regulated upon activation normal T cell expressed and secreted (RANTES)
Database Links
Ensembl Gene ENSG00000161570 (Hs)
Entrez Gene 6352 (Hs)
GtoPdb PubChem SID 135651690
Human Protein Atlas ENSG00000161570 (Hs)
OMIM 187011
RefSeq Protein NP_002976
UniProtKB P13501 (Hs)
Wikipedia CCL5 (Hs)
CCL5 (also known as RANTES- and acronym for regulated on activation, normal T cell expressed and secreted) is a CC family chemokine, that has HIV suppressive activity, as do the related CD8+ T cell chemokines CCL3 and CCL4.
Medical Relevance
Many diseases have been associated to certain RANTES polymorphisms. For further information see GeneRIFs