cromoglicic acid

Ligand id: 7608

Name: cromoglicic acid

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 8
Topological polar surface area 165.89
Molecular weight 468.07
XLogP 0.99
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1984))
IUPAC Name
5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid
International Nonproprietary Names
INN number INN
2427 cromoglicic acid
Synonyms
cromoglycate | cromolyn | cromolyn sodium | FPL-670 | Intal® | Opticrom® | sodium cromoglicate
Database Links
CAS Registry No. 16110-51-3
ChEBI CHEBI:59773
ChEMBL Ligand CHEMBL428880
DrugBank Ligand DB01003
PubChem CID 2882
Search Google for chemical match using the InChIKey IMZMKUWMOSJXDT-UHFFFAOYSA-N
Search Google for chemicals with the same backbone IMZMKUWMOSJXDT
Search PubMed clinical trials cromoglicic acid
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Search UniChem for chemical match using the InChIKey IMZMKUWMOSJXDT-UHFFFAOYSA-N
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Wikipedia Cromoglicic acid
Comments
Cromoglicic acid is regarded as a mast cell stabilising drug, although its exact mechanism of action appears to be much more complicated. Clinical use in asthma has largely been replaced by the more convenient leukotriene receptor antagonists.