benzonatate

Ligand id: 7611

Name: benzonatate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 12
Hydrogen bond donors 1
Rotatable bonds 33
Topological polar surface area 121.4
Molecular weight 603.36
XLogP 1.35
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1958))
IUPAC Name
2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-butylaminobenzoate
International Nonproprietary Names
INN number INN
651 benzonatate
Synonyms
Tessalon® | Zonatuss®
Database Links
CAS Registry No. 104-31-4
ChEBI CHEBI:3032
ChEMBL Ligand CHEMBL1374379
DrugBank Ligand DB00868
GtoPdb PubChem SID 223365946
PubChem CID 7699
Search Google for chemical match using the InChIKey MAFMQEKGGFWBAB-UHFFFAOYSA-N
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Search UniChem for chemical match using the InChIKey MAFMQEKGGFWBAB-UHFFFAOYSA-N
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Wikipedia Benzonatate
Comments
Benzonatate is a non-narcotic antitussive. It is classified as a butylamine compound, and has structural similatities to ester type local anesthetics (e.g. Procaine and tetracaine). It has reduced abuse potential compared to opioid-like antitussives.