cariprazine

Ligand id: 7671

Name: cariprazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Topological polar surface area 38.82
Molecular weight 426.2
XLogP 3.36
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (2015))
IUPAC Name
3-[4-[2-[4-(2,3-dichlorophenyl)piperazin-1-yl]ethyl]cyclohexyl]-1,1-dimethylurea
International Nonproprietary Names
INN number INN
8920 cariprazine
Synonyms
RGH 188 | RGH-188 | Vraylar®
Database Links
CAS Registry No. 839712-12-8
ChEMBL Ligand CHEMBL2028019
PubChem CID 11154555
Search Google for chemical match using the InChIKey KPWSJANDNDDRMB-QAQDUYKDSA-N
Search Google for chemicals with the same backbone KPWSJANDNDDRMB
Search PubMed clinical trials cariprazine
Search PubMed titles cariprazine
Search PubMed titles/abstracts cariprazine
Search UniChem for chemical match using the InChIKey KPWSJANDNDDRMB-QAQDUYKDSA-N
Search UniChem for chemicals with the same backbone KPWSJANDNDDRMB
Wikipedia Cariprazine
Comments
Cariprazine is an antipsychotic. Our structure was drawn from the INN record which shows stereo-chemistry for this compound. PubChem have a record only for the non-chiral molecule, with CID 11154555. The compound is liphophilic meaning that it can easily cross the blood-brain barrier, to reach its site of action [2].