moxetumomab pasudotox

Ligand id: 7675

Name: moxetumomab pasudotox

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9236 moxetumomab pasudotox
Synonyms
CAT-8015
GCR-8015
HA22
Database Links
Specialist databases
IMGT/mAb-DB 198
Other databases
ChEMBL Ligand CHEMBL1743043
Search PubMed clinical trials moxetumomab pasudotox
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Wikipedia Moxetumomab pasudotox
Comments
Peptide sequence information for this antibody is available from its IMGT/mAb-DB link. The moxetumomab monoclonal has been mutated to increase affinity for CD22 [6] (patent WO2003027135[1]), and the antibody is fused to a 38 KDa fragment of Pseudomonas exotoxin-A (PE38) [2,4] (patent US7982011 [5]). The Uniprot accession for Pseudomonas exotoxin-A is P11439.